Cancer: One trigger can make skin melanoma more aggressive and deadly


The research opens up new opportunities for treatment and diagnosis.

The researchers used a drug that inhibits NGFR and found that it helped to deter the cancer from spreading in mice.

“This drug needs a lot of testing,” Dr Lyden explained.

“Eventually, I think an NGFR inhibitor could be used in the clinical setting.

“We also would like to determine if we can use a simple blood test to see whether exosomes are carrying NGFR.

“This would help doctors to look at exosome NGFR over time during therapy to see how treatments should be adjusted.”



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