Elsewhere, two newly-promoted sides are predicted to face off, with Brentford hosting Watford.
The other promoted side, Norwich City, start by hosting Everton, who will be one of a few clubs starting the season with new managers.
Leicester City and West Ham United, the Premier League’s Europa League representatives next season, have both been predicted home games.
According to the supercomputer, the Foxes will host Newcastle United, whilst West Ham welcome Aston Villa to the London Stadium in a tasty opener.
Find the Express Sport supercomputer’s entire opening day fixture list below.